You know, now that I think about it could have clarified that a lot more, that was supposed to be angle. Not percentage of grind, although I haven't totally looking into 50/50 sharpening a single bevel knife, I'm sure it would pretty much just change the geometry pending your angles are consistent. I had a lot on my mind yesterday.
Let's say you grind the right side of the knife at 17 degrees, but you were really shooting for 15. You get a burr then flip to the left side. You sharpen the left side at 15 degrees, and get a burr on that side. After you get a burr on both sides you reduce pressure. Now, you get back to the right side and you reduce pressure. When you reduce pressure your angle might change to 15 degrees instead of 17 like when you were using more pressure. When you do this you aren't even hitting the edge anymore, but you may not realize it because you aren't familiar enough with the sound or stone feedback of hitting the edge, whatever it may be. So, if you don't hit the edge on the right side, but then keep hitting the edge on the other side it will push the edge over. An edge at low grit will still cut like this however.
This is just an example of one scenario, I was just trying to illustrate one of the many problems people might encounter while sharpening.